Training & Experience
THOMAS A. TIRONE, M.D.
Clearwater Surgical Associates
1106 Druid Rd. South Suite 301
Clearwater FL, 33756
(727) 446-5681 Telephone
(727) 461-6258 FAX:
http://www.clearwatersurgicalassociates.com
E-mail: info@clearwatersurgicalassociates.com
BOARD CERTIFICATION:
American Board of Surgery,
Certificate Number 48791, February 2004.
LICENSURE:
ME97995, State of Florida, February, 2007.
0101234889, State of Virginia, June, 2003.
PREVIOUS EMPLOYMENT:
St Petersburg General Surgery LLC.
6450 38th Avenue North, Suite 410
St Petersburg, FL 33710
(727) 344 – 4200
(727) 344 4221 Fax
March 2007 – Present.
Carilion Surgical Care Martinsville
445 Commonwealth Boulevard
Martinsville, VA 24112
(276) 638-6046
August 2004 – February 2007.
Solo Private Practice
445 Commonwealth Boulevard
Martinsville, VA 24112
(276) 638-6046
August 2003 – July 2004.
EDUCATION:
MD, Tulane University School of Medicine
New Orleans, Louisiana.
July 1994 – May 1996.
Graduated 8th in class of 150 students.
MD, Strich School of Medicine, Loyola University at Chicago
Maywood, Illinois.
July 1992 – June 1994.
BA, The Johns Hopkins University
Baltimore, Maryland.
September 1988 – December 1991.
Major: Natural Sciences.
POSTGRADUATE TRAINING:
Michael E. DeBakey Department of Surgery
Baylor College of Medicine.
One Baylor Plaza, Houston, TX. 77030.
Chairman: F.C. Brunicardi, M.D.
General Surgery: June 1996 – July 2003.
Internship: June 1996 – June 1997.
Research Fellowship July 1998 – June 2000.
Chief Resident: July 2002 – July 2003.
RESEARCH:
Research Fellow, Laboratory of F. Charles Brunicardi, M.D.,
Department of Surgery Baylor College of Medicine.
July 1998 – June 2000.
Projects: “Selective Cell Targeting Utilizing Promoter
Driven Thymidine Kinase”.
“Delta to Beta Cell Endocrine Axis”.
Department of Surgery, Tulane University School of Medicine.
June – August 1995.
Project: “Correction of Congenital Indirect Hyberbilirubinemia
by Small Intestinal Transplantation.”
Medley, MN., Hooker, RL., Rabinowitz,S., Holton, R., Jaffe, BM.
Published in The American Journal of Surgery, 169:20, 1995.
Mentor, Bernard M. Jaffe, M.D.
GRANTS:
1. Advanced Research Program, Advanced Research Technology Program “Selective Beta Cell Targeting with Promoter Driven Thymidine Kinase.”
(F. Charles Brunicardi, M.D. PI).
January 2000 – 2002: $200,000.
2. National Institute of Health (DK-07696)
“Delta to Beta Cell Endocrine Axis.”
July1998 – June 1999: $35,000.
AWARDS & ACTIVITIES:
1. Member of Quality Assurance Committee, St Petersburg General Hospital, St Petersburg Florida, September 2007.
2. Section Chief General Surgery, Memorial Hospital of Martinsville and Henry County, Martinsville Virginia, January 2006.
3. American College of Surgeons Cancer Liaison Physician, Memorial Hospital of Martinsville and Henry County, Martinsville Virginia, October 2005.
4. Member of Critical Care Committee, Memorial Hospital of Martinsville and Henry County, Martinsville Virginia, January 2004.
5. Employee of the Month, Veterans Affairs Hospital, Houston Texas, August 2001.
6. Ross Resident Research Awards, Society of Surgeons of the Alimentary Tract, 2000 & 2001.
7. Alpha Omega Alpha Honor Medical Society Member, 1996.
8. Tulane University School of Medicine, W. Clifford Newman Award, 1996.
9. Honors Surgery Course July, 1995.
10. Teaching Assistant, The Johns Hopkins University, 1990.
11. The Johns Hopkins University Varsity Football Team, 1988.
12. Scholar Athlete Award 1988.
PROFESSIONAL SOCIETIES:
1. Member The American Society of Breast Surgeons, 2005.
2. Fellow American College of Surgeons, 2005.
3. DeBakey Surgical Society, 2003.
4. Member Society of Surgeons of the Alimentary Tract, 2001.
5. Fellow Association for Academic Surgeons, 1998.
6. Candidate Fellow American College of Surgeons, 1996 – 2003.
7. Member, Alpha Delta Phi Fraternity, 1989.
PUBLICATIONS:
1. TA Tirone, XP Wang, NS Templeton, T Lee, W Fisher, FC Brunicardi, “Cell-specific cytotoxicity of human pancreatic adenocarcinoma cells using rat insulin promoter thymidine kinase-directed gene therapy.”
World J Surg. 2004 Aug;28(8):826-33.
2. TA Tirone, M. Norman, S Moldovan, FJ DeMayo, XP Wang, and FC Brunicardi, “Pancreatic somatostatin inhibits insulin secretion via SSTR-5 in the isolated perfused mouse pancreas model.”
Pancreas. 2003 Apr;26(3):e67-73.
3. TA Tirone, SP Fagan, NS Templeton, X Wang, FC Brunicardi, “Insulinoma-induced hypoglycemic death in mice is prevented with beta cell-specific gene therapy.”
Ann Surg. 2001 May;233(5):603-11.
4. TA Tirone, FC Brunicardi, “Overview of glucose regulation.”
World J Surg. 2001 Apr;25(4):461-7.
5. TA Tirone, FC Brunicardi, “Gallstones and the Billiary Tract.”
Current Practice of Medicine, 1999 Dec;2(12):2447-2452.
Abstracts:
1. T.A. Tirone, T Lee, L Nguyen, and FC Brunicardi, “Human Ductal Pancreatic Adenocarcinoma (PDA) Cells That Express PDX-1 Can Be Targeted With a Rat Promoter Thymidine Kinase Construct.”
The Journal of Surgical Research. 2000 October.
2. Thomas A. Tirone, Stefan Moldovan, Michael Norman, Juan Lechago, Franco J. DeMayo, F. Charles Brunicardi “Alterations in Insulin Secretion in the Somatostatin Subtype Receptor 5 Knockout Mouse Using the Isolated Perfused Mouse Pancreas Model.”
Owen H. Wangensteen Surgical Forum. 2000 Oct;L(I):44-45.
3. TA Tirone, SP Fagan, MK Ray, FC Brunicardi, “Beta Cell Specific
Cytotoxicity Using a Rat Insulin Promoter Thymidine Kinase Construct.” The Journal of Surgical Research. 1999 October.
ABSTRACTS:
1. TA Tirone, S Moldovan, M Norman, F J DeMayo, F. Charles Brunicardi, “Intraislet Somatostatin Inhibits Insulin Secretion Via SSTR5 In The Isolated Perfused Mouse Pancreas Model.”
American Gastroenterological Association. May 2001
2. TA Tirone, X Wang, NS Templeton, FC Brunicardi, “Human Ductal Pancreatic Adenocarcinoma Cells Can Be Targeted and Destroyed by a Rat Insulin Promoter Thymidine Kinase Construct, In Vivo.”
Society of Surgeons of the Alimentary Tract. May 2001.
3. TA Tirone, X Wang, NS Templeton, FC Brunicardi, “Human ductal pancreatic adenocarcinoma cells can be targeted and destroyed by a rat insulin promoter-thymidine kinase construct, in vitro and in vivo.”
Pancreas Club, Inc. May 2001
4. TA Tirone, S Moldovan, M Norman, F J DeMayo, F. Charles Brunicardi, “Intraislet Somatostatin Inhibits Insulin Secretion Via SSTR5 In The Isolated Perfused Mouse Pancreas Model.”
American College of Surgeons, South Texas Chapter. March 2001.
5. T.A. Tirone, T Lee, L Nguyen, NS Templeton, and FC Brunicardi, “Human Pancreatic Adenocarcinoma Cells (PDA) can be Targeted by a Rat Insulin Promoter Thymidine Kinase Construct In Vitro and In Vivo.”
Resident’s Conference The Society of University Surgeons.
February 2001.
6. TA Tirone, SP Fagan, NS Templeton, X Wang, FC Brunicardi, “Insulinoma-induced hypoglycemic death in mice is prevented with beta cell-specific gene therapy.”
Southern Surgical Association. December 2000. Won Shipley Award.
7. T.A. Tirone, T Lee, L Nguyen, NS Templeton, and FC Brunicardi, “Human Ductal Pancreatic Adenocarcinoma Cells Can Be Targeted In Vivo Using a Rat Insulin Promoter Thymidine Kinase Construct.”
Michael E. DeBakey International Surgical Society XIIIth Congress. November 2000.
8. T.A. Tirone, T Lee, L Nguyen, and FC Brunicardi, “Human Ductal Pancreatic Adenocarcinoma (PDA) Cells That Express PDX-1 Can Be Targeted With a Rat Promoter Thymidine Kinase Construct.”
Association of Academic Surgeons. November 2000.
9. Thomas A. Tirone, Stefan Moldovan, Michael Norman, Juan Lechago, Franco J. DeMayo, F. Charles Brunicardi “Alterations in Insulin Secretion in the Somatostatin Subtype Receptor 5 Knockout Mouse Using the Isolated Perfused Mouse Pancreas Model.”
American College of Surgeons. October 2000.
10. TA Tirone, W Fisher, L Bromtom, FC Brunicardi, “PANC-1 Cells can be Targeted In Vitro with a Rat Insulin Promoter Thymidine Kinase construct.”
Society of Surgeons of the Alimentary Tract. May 2000.
11. TA Tirone, FC Brunicardi, W Fisher, “Human Pancreatic
Cancer Targeting Using A Rat Insulin Promoter Thymidine Kinase Construct.”
American College of Surgeons, South Texas Chapter. February 2000.
12. TA Tirone, SP Fagan, MK Ray, FC Brunicardi, “Beta Cell Specific
Cytotoxicity Using a Rat Insulin Promoter Thymidine Kinase Construct.”
Association of Academic Surgeons. November 1999.
PRESENTATIONS:
1. Community Lecture Series; H2U, St Petersburg General Hospital.
“Breast Cancer and Early Detection.”
St Petersburg, FL. October & November 2007.
2. Grand Rounds, St Petersburg General Hospital.
“Advances in Breast Cancer Care.”
St Petersburg, FL. September 2007.
3. Grand Rounds, Psalms of Pasadena Hospital.
“Advances in the Treatment of Breast Cancer.”
St Petersburg, FL. September 2007.
4. Grand Rounds, Memorial Hospital of Martinsville and Henry County.
“Current Concepts in Breast Disease.”
Martinsville, VA. March 2004.
5. American Gastroenterological Association.
“Intraislet Somatostatin Inhibits Insulin Secretion Via SSTR5 In The Isolated Perfused Mouse Pancreas Model.”
Atlanta, GA. May 2001.
6. Society of Surgeons of the Alimentary Tract, Ross Research Symposium.
“Human Ductal Pancreatic Adenocarcinoma Cells Can Be Targeted and Destroyed by a Rat Insulin Promoter Thymidine Kinase Construct, In Vivo.”
Atlanta, GA. May 2001.
7. Pancreas Club, Inc.
“Human ductal pancreatic adenocarcinoma cells can be targeted and destroyed by a rat insulin promoter-thymidine kinase construct, in vitro and in vivo.”
Atlanta, GA. May 2001.
8. American College of Surgeons, South Texas Chapter.
“Intraislet Somatostatin Inhibits Insulin Secretion Via SSTR5 In The Isolated Perfused Mouse Pancreas Model.”
San Antonio, TX. March 2001.
9. Resident’s Conference The Society of University Surgeons.
“Human Pancreatic Adenocarcinoma Cells (PDA) can be Targeted by a Rat Insulin Promoter Thymidine Kinase Construct In Vitro and In Vivo.”
Chicago, IL. February 2001
10. Michael E. DeBakey International Surgical Society XIIIth Congress.
“Human Ductal Pancreatic Adenocarcinoma Cells Can Be Targeted In Vivo Using a Rat Insulin Promoter Thymidine Kinase Construct.”
Houston, TX. November 2000.
11. Association of Academic Surgeons.
“Human Ductal Pancreatic Adenocarcinoma (PDA) Cells That Express PDX-1 Can Be Targeted With a Rat Promoter Thymidine Kinase Construct.”
Tampa, FL. November 2000.
12. American College of Surgeons.
“Alterations in Insulin Secretion in the Somatostatin Subtype Receptor 5 Knockout Mouse Using the Isolated Perfused Mouse Pancreas Model.”
Chicago, IL. October 200.
13. Society of Surgeons of the Alimentary Tract, Ross Research Symposium.
“PANC-1 Cells can be Targeted In Vitro with a Rat Insulin Promoter Thymidine Kinase construct.”
San Diego, CA. May 2000.
14. American College of Surgeons, South Texas Chapter.
“Human Pancreatic Cancer Targeting Using A Rat Insulin Promoter Thymidine Kinase Construct.”
San Antonio, TX. February 2000.
15. Department of Surgery Grand Rounds, Baylor College of Medicine.
“Human Pancreatic Ductal Carcinoma Cells (PANC-1) Can Be Targeted In Vitro, With A Rat Insulin Promoter Thymidine Kinase Construct.”
Houston, TX. December 1999.
16. Association for Academic Surgeons.
“Beta Cell Specific Cytotoxicity Using a Rat Insulin Promoter Thymidine Kinase Construct.”
Philadelphia, PA. November 1999.
17. Department of Surgery Grand Rounds, Baylor College of Medicine. “Selective Beta Cell Targeting.”
Houston, TX. February, 1999.
18. Department of Surgery Basic Science Lecture, Baylor College of Medicine.
“Surgical Anatomy of The Thyroid.”
Houston, TX. April 1997.
19. Department of Surgery Basic Science Lecture, Baylor College of Medicine.
“The Basic Science of Wound Healing.”
Houston, TX. December 1996.
SCIENTIFIC POSTERS:
1. Society of Surgeons of the Alimentary Tract.
“ Human Ductal Pancreatic Adenocarcinoma Cells Can Be Targeted and Destroyed by a Rat Insulin Promoter Thymidine Kinase Construct, In Vivo.”
Atlanta, Georgia. May 2001. Poster of distinction.
2. Society of Surgeons of the Alimentary Tract.
“PANC-1 Cells can be Targeted In Vitro with a Rat Insulin Promoter Thymidine Kinase construct.”
San Diego, CA. May 2000.